Pharmacotherapeutics for Nurse Practitioner Prescribers 3rd Edition by Teri Moser Woo – Test Bank
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Chapter 3: Rational Drug Selection
 
Multiple Choice
Identify the choice that best completes the statement or answers
the question.
 
____    1.   An NP would prescribe the
liquid form of ibuprofen for a 6 year old because:
| 
   A.  | 
  
   Drugs given in liquid form
  are less irritating to the stomach  | 
 
| 
   B.  | 
  
   A 6 year old may have
  problems swallowing a pill  | 
 
| 
   C.  | 
  
   Liquid forms of medication
  eliminate the concern for first-pass effect  | 
 
| 
   D.  | 
  
   Liquid ibuprofen does not
  have to be dosed as often as tablet form  | 
 
 
 
____    2.   In deciding which of
multiple drugs used to use to treat a condition, the NP chooses Drug A because
it:
| 
   A.  | 
  
   Has serious side effects
  and it is not being used for a life-threatening condition  | 
 
| 
   B.  | 
  
   Will be taken twice daily
  and will be taken at home  | 
 
| 
   C.  | 
  
   Is expensive, and is not
  covered by health insurance  | 
 
| 
   D.  | 
  
   None of these are important
  in choosing a drug  | 
 
 
 
____    3.   A client asks the NP about
the differences in drug effects between men and women. What is known about the
differences between the pharmacokinetics of men and women?
| 
   A.  | 
  
   Body temperature varies
  between men and women  | 
 
| 
   B.  | 
  
   Muscle mass is greater in
  women  | 
 
| 
   C.  | 
  
   Percentage of fat differs
  between genders  | 
 
| 
   D.  | 
  
   Proven subjective factors
  exist between the genders  | 
 
 
 
____    4.   The first step in the
prescribing process according to the World Health Organization is:
| 
   A.  | 
  
   Choosing the treatment  | 
 
| 
   B.  | 
  
   Educating the patient about
  the medication  | 
 
| 
   C.  | 
  
   Diagnosing the patient’s
  problem  | 
 
| 
   D.  | 
  
   Starting the treatment  | 
 
 
 
____    5.   Treatment goals in
prescribing should:
| 
   A.  | 
  
   Always be curative  | 
 
| 
   B.  | 
  
   Be patient-centered  | 
 
| 
   C.  | 
  
   Be convenient for the
  provider  | 
 
| 
   D.  | 
  
   Focus on the cost of
  therapy  | 
 
 
 
____    6.   The therapeutic goals when
prescribing include(s):
| 
   A.  | 
  
   Curative  | 
 
| 
   B.  | 
  
   Palliative  | 
 
| 
   C.  | 
  
   Preventive  | 
 
| 
   D.  | 
  
   All of the above  | 
 
 
 
____    7.   When determining drug
treatment the NP prescriber should:
| 
   A.  | 
  
   Always use evidence-based
  guidelines  | 
 
| 
   B.  | 
  
   Individualize the drug
  choice for the specific patient  | 
 
| 
   C.  | 
  
   Rely on his or her
  experience when prescribing for complex patients  | 
 
| 
   D.  | 
  
   Use the newest drug on the
  market for the condition being treated  | 
 
 
 
____    8.   Patient education
regarding prescribed medication includes:
| 
   A.  | 
  
   Instructions written at the
  high school reading level  | 
 
| 
   B.  | 
  
   Discussion of expected
  adverse drug reactions  | 
 
| 
   C.  | 
  
   How to store leftover
  medication such as antibiotics  | 
 
| 
   D.  | 
  
   Verbal instructions always
  in English  | 
 
 
 
____    9.   Passive monitoring of drug
effectiveness includes:
| 
   A.  | 
  
   Therapeutic drug levels  | 
 
| 
   B.  | 
  
   Adding or subtracting
  medications from the treatment regimen  | 
 
| 
   C.  | 
  
   Ongoing provider visits  | 
 
| 
   D.  | 
  
   Instructing the patient to report
  if the drug is not effective  | 
 
 
 
____  10.   Pharmacokinetic factors that affect
prescribing include:
| 
   A.  | 
  
   Therapeutic index  | 
 
| 
   B.  | 
  
   Minimum effective
  concentration  | 
 
| 
   C.  | 
  
   Bioavailability  | 
 
| 
   D.  | 
  
   Ease of titration  | 
 
 
 
____  11.   Pharmaceutical promotion may affect
prescribing. To address the impact of pharmaceutical promotion, the following
recommendations have been made by the Institute of Medicine:
| 
   A.  | 
  
   Conflicts of interest and
  financial relationships should be disclosed by those providing education.  | 
 
| 
   B.  | 
  
   Providers should ban all
  pharmaceutical representatives from their office setting.  | 
 
| 
   C.  | 
  
   Drug samples should be used
  for patients who have the insurance to pay for them, to ensure the patient
  can afford the medication.  | 
 
| 
   D.  | 
  
   Providers should only accept
  low-value gifts, such as pens and pads of paper, from the pharmaceutical
  representative.  | 
 
 
Chapter 3: Rational Drug Selection
Answer Section
 
MULTIPLE CHOICE
 
1.    ANS: 
B                   
PTS:   1
 
2.    ANS: 
B                   
PTS:   1
 
3.    ANS: 
C                   
PTS:   1
 
4.    ANS: 
C                   
PTS:   1
 
5.    ANS: 
B                   
PTS:   1
 
6.    ANS: 
D                   
PTS:   1
 
7.    ANS: 
B                   
PTS:   1
 
8.    ANS: 
B                   
PTS:   1
 
9.    ANS: 
D                   
PTS:   1
 
10.  ANS: 
C                   
PTS:   1
 
11.  ANS: 
A                   
PTS:   1
 
Chapter 4: Legal and Professional Issues in Prescribing
 
Multiple Choice
Identify the choice that best completes the statement or answers
the question.
 
____    1.   The U.S. Food and Drug
Administration (FDA) regulates:
| 
   A.  | 
  
   Prescribing of drugs by MDs
  and NPs  | 
 
| 
   B.  | 
  
   The official labeling for
  all prescription and over-the-counter drugs  | 
 
| 
   C.  | 
  
   Off-label recommendations
  for prescribing  | 
 
| 
   D.  | 
  
   Pharmaceutical educational
  offerings  | 
 
 
 
____    2.   The U.S. Food and Drug
Administration (FDA) approval is required for:
| 
   A.  | 
  
   Medical devices, including
  artificial joints  | 
 
| 
   B.  | 
  
   Over-the-counter vitamins  | 
 
| 
   C.  | 
  
   Herbal products, such as St
  John’s Wort  | 
 
| 
   D.  | 
  
   Dietary supplements, such
  as Ensure  | 
 
 
 
____    3.   An Investigational New
Drug (IND) is filed with the FDA:
| 
   A.  | 
  
   When the manufacturer has
  completed Phase III trials  | 
 
| 
   B.  | 
  
   When a new drug is
  discovered  | 
 
| 
   C.  | 
  
   Prior to animal testing of
  any new drug entity  | 
 
| 
   D.  | 
  
   Prior to human testing of
  any new drug entity  | 
 
 
 
____    4.   Phase IV clinical trials
in the United States are also known as:
| 
   A.  | 
  
   Human bioavailability
  trials  | 
 
| 
   B.  | 
  
   Post-marketing research  | 
 
| 
   C.  | 
  
   Human safety and efficacy
  studies  | 
 
| 
   D.  | 
  
   The last stage of animal
  trials before the human trials begin  | 
 
 
 
____    5.   Off-label prescribing is:
| 
   A.  | 
  
   Regulated by the FDA  | 
 
| 
   B.  | 
  
   Illegal by NPs in all
  states (provinces)  | 
 
| 
   C.  | 
  
   Legal if there is
  scientific evidence for the use  | 
 
| 
   D.  | 
  
   Regulated by the Drug Enforcement
  Administration (DEA)  | 
 
 
 
____    6.   The U.S. Drug Enforcement
Administration (DEA):
| 
   A.  | 
  
   Registers manufacturers and
  prescribers of controlled substances  | 
 
| 
   B.  | 
  
   Regulates NP prescribing at
  the state level  | 
 
| 
   C.  | 
  
   Sanctions providers who prescribe
  drugs off-label  | 
 
| 
   D.  | 
  
   Provides prescribers with a
  number they can use for insurance billing  | 
 
 
 
____    7.   Drugs that are designated
Schedule II by the DEA:
| 
   A.  | 
  
   Are known teratogens during
  pregnancy  | 
 
| 
   B.  | 
  
   May not be refilled; a new
  prescription must be written  | 
 
| 
   C.  | 
  
   Have a low abuse potential  | 
 
| 
   D.  | 
  
   May be dispensed without a
  prescription unless regulated by the state  | 
 
 
 
____    8.   Precautions that should be
taken when prescribing controlled substances include:
| 
   A.  | 
  
   Faxing the prescription for
  a Schedule II drug directly to the pharmacy  | 
 
| 
   B.  | 
  
   Using tamper-proof paper
  for all prescriptions written for controlled drugs  | 
 
| 
   C.  | 
  
   Keeping any pre-signed
  prescription pads in a locked drawer in the clinic  | 
 
| 
   D.  | 
  
   Using only numbers to
  indicate the amount of drug to be prescribed  | 
 
 
 
____    9.   Strategies prescribers can
use to prevent misuse of controlled prescription drugs include:
| 
   A.  | 
  
   Use of chemical dependency
  screening tools  | 
 
| 
   B.  | 
  
   Firm limit-setting
  regarding prescribing controlled substances  | 
 
| 
   C.  | 
  
   Practicing “just say no” to
  deal with patients who are pushing the provider to prescribe controlled
  substances  | 
 
| 
   D.  | 
  
   All of the above  | 
 
 
 
____  10.   Behaviors predictive of addiction to
controlled substances include:
| 
   A.  | 
  
   Stealing or borrowing
  another patient’s drugs  | 
 
| 
   B.  | 
  
   Requiring increasing doses
  of opiates for pain associated with malignancy  | 
 
| 
   C.  | 
  
   Receiving refills of a
  Schedule II prescription on a regular basis  | 
 
| 
   D.  | 
  
   Requesting that only their
  own primary care provider prescribe for them  | 
 
 
 
____  11.   Medication agreements or “Pain
Medication Contracts” are recommended to be used:
| 
   A.  | 
  
   Universally for all
  prescribing for chronic pain  | 
 
| 
   B.  | 
  
   For patients who have
  repeated requests for pain medication  | 
 
| 
   C.  | 
  
   When you suspect a patient
  is exhibiting drug-seeking behavior  | 
 
| 
   D.  | 
  
   For patients with pain
  associated with malignancy  | 
 
 
 
____  12.   A prescription needs to be written
for:
| 
   A.  | 
  
   Legend drugs  | 
 
| 
   B.  | 
  
   Most controlled drugs  | 
 
| 
   C.  | 
  
   Medical devices  | 
 
| 
   D.  | 
  
   All of the above  | 
 
 
Chapter 4: Legal and Professional Issues in Prescribing
Answer Section
 
MULTIPLE CHOICE
 
1.    ANS: 
B                   
PTS:   1
 
2.    ANS: 
A                   
PTS:   1
 
3.    ANS: 
D                   
PTS:   1
 
4.    ANS: 
B                   
PTS:   1
 
5.    ANS: 
C                   
PTS:   1
 
6.    ANS: 
A                   
PTS:   1
 
7.    ANS: 
B                   
PTS:   1
 
8.    ANS: 
B                   
PTS:   1
 
9.    ANS: 
D                   
PTS:   1
 
10.  ANS: 
A                   
PTS:   1
 
11.  ANS: 
A                   
PTS:   1
 
12.  ANS: 
D                   
PTS:   1
 
Chapter 50: Pediatric Patients
 
Multiple Choice
Identify the choice that best completes the statement or answers
the question.
 
____    1.   The Pediatric Research
Equity Acts requires:
| 
   A.  | 
  
   All children be provided equal
  access to drug research trials  | 
 
| 
   B.  | 
  
   Children to be included in
  the planning phase of new drug development  | 
 
| 
   C.  | 
  
   That pediatric drug trials
  guarantee children of multiple ethnic groups are included  | 
 
| 
   D.  | 
  
   All applications for new
  active ingredients, new indications, new dosage forms, or new routes of
  administration require pediatric studies  | 
 
 
 
____    2.   The Best Pharmaceuticals
for Children Act:
| 
   A.  | 
  
   Includes a pediatric
  exclusivity rule which extends the patent on drugs studied in children  | 
 
| 
   B.  | 
  
   Establishes a committee
  that writes guidelines for pediatric prescribing  | 
 
| 
   C.  | 
  
   Provides funding for new
  drug development aimed at children  | 
 
| 
   D.  | 
  
   Encourages manufacturers
  specifically to develop pediatric formulations  | 
 
 
 
____    3.   The developmental
variation in Phase I enzymes has what impact on pediatric prescribing?
| 
   A.  | 
  
   None, Phase I enzymes are
  stable throughout childhood.  | 
 
| 
   B.  | 
  
   Children should always be
  prescribed lower than adult doses per weight due to low enzyme activity until
  puberty.  | 
 
| 
   C.  | 
  
   Children should always be
  prescribed higher than adult doses per weight due to high enzyme activity.  | 
 
| 
   D.  | 
  
   Prescribing dosages will
  vary based on the developmental activity of each enzyme, at times requiring
  lower than adult doses and other times higher than adult doses based on the
  age of the child.  | 
 
 
 
____    4.   Developmental variation in
renal function has what impact on prescribing for infants and children?
| 
   A.  | 
  
   Lower doses of renally
  excreted drugs may be prescribed to infants younger than age 6 months.  | 
 
| 
   B.  | 
  
   Higher doses of water
  soluble drugs may need to be prescribed due to increased renal excretion.  | 
 
| 
   C.  | 
  
   Renal excretion rates have
  no impact on prescribing.  | 
 
| 
   D.  | 
  
   Parents need to be
  instructed on whether drugs are renally excreted or not.  | 
 
 
 
____    5.   Topical corticosteroids
are prescribed cautiously in young children due to:
| 
   A.  | 
  
   They may cause an intense
  hypersensitivity reaction  | 
 
| 
   B.  | 
  
   Hypothalamic-pituitary-adrenal
  (HPA) axis suppression  | 
 
| 
   C.  | 
  
   Corticosteroids are less
  effective in young children  | 
 
| 
   D.  | 
  
   Young children may
  accumulate corticosteroids leading to toxic levels  | 
 
 
 
____    6.   Liza is breastfeeding her
2-month-old son and has an infection that requires an antibiotic. What drug
factors influence the effect of the drug on the infant?
| 
   A.  | 
  
   Maternal drug levels  | 
 
| 
   B.  | 
  
   Half-life  | 
 
| 
   C.  | 
  
   Lipid-solubility  | 
 
| 
   D.  | 
  
   All of the above  | 
 
 
 
____    7.   Drugs that are absolutely
contraindicated in lactating women include:
| 
   A.  | 
  
   Selective serotonin
  reuptake inhibitors  | 
 
| 
   B.  | 
  
   Antiepileptic drugs such as
  carbamazepine  | 
 
| 
   C.  | 
  
   Antineoplastic drugs such
  as methotrexate  | 
 
| 
   D.  | 
  
   All of the above  | 
 
 
 
____    8.   Zia is a 4 month old with
otitis media. Education of his parents regarding administering oral antibiotics
to an infant includes:
| 
   A.  | 
  
   How to administer an oral
  drug using a medication syringe  | 
 
| 
   B.  | 
  
   Mixing the medication with
  a couple ounces of formula and putting it in a bottle  | 
 
| 
   C.  | 
  
   Discontinuing the
  antibiotic if diarrhea occurs  | 
 
| 
   D.  | 
  
   Calling for an antibiotic
  change if the infant chokes and sputters during administration  | 
 
 
 
____    9.   To increase adherence in
pediatric patients a prescription medication should:
| 
   A.  | 
  
   Have a short half-life  | 
 
| 
   B.  | 
  
   Be the best tasting of the
  effective drugs  | 
 
| 
   C.  | 
  
   Be the least concentrated
  form of the medication  | 
 
| 
   D.  | 
  
   Be administered 3 or 4
  times a day  | 
 
 
 
____  10.   Janie is a 5-month-old breastfed
infant with a fever. Treatment for her fever may include:
| 
   A.  | 
  
   “Baby” aspirin  | 
 
| 
   B.  | 
  
   Acetaminophen suppository  | 
 
| 
   C.  | 
  
   Ibuprofen suppository  | 
 
| 
   D.  | 
  
   Alternating acetaminophen
  and ibuprofen  | 
 
 
Chapter 50: Pediatric Patients
Answer Section
 
MULTIPLE CHOICE
 
1.    ANS: 
D                   
PTS:   1
 
2.    ANS: 
B                   
PTS:   1
 
3.    ANS: 
D                   
PTS:   1
 
4.    ANS: 
A                   
PTS:   1
 
5.    ANS: 
B                   
PTS:   1
 
6.    ANS: 
D                   
PTS:   1
 
7.    ANS: 
C                   
PTS:   1
 
8.    ANS: 
A                   
PTS:   1
 
9.    ANS: 
B                   
PTS:   1
 
10.  ANS: 
B                   
PTS:   1
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